Author/Authors :
R. Cristescu، نويسنده , , C. Popescu، نويسنده , , A.C. Popescu، نويسنده , , S. Grigorescu، نويسنده , , L. Duta، نويسنده , , Shyh-Lin Tsao and I.N. Mihailescu، نويسنده , , G. Caraene، نويسنده , , R. Albulescu، نويسنده , , L. Albulescu، نويسنده , , A. Andronie، نويسنده , , I. Stamatin، نويسنده , , Despina A. Ionescu، نويسنده , , D. Mihaiescu and A. Moldovan، نويسنده , , T. Buruiana، نويسنده , , D.B. Chrisey، نويسنده ,
Abstract :
We report thin film deposition of polyvinyl alcohol functionalized with carboxylic groups bound to aromatic nucleus (PVACOOH) by matrix-assisted pulsed laser evaporation (MAPLE). We used a KrF* excimer laser source (λ = 248 nm, τ = 25 ns, image). The obtained thin films have been investigated by FTIR, AFM, and in vitro tests. We identified the best compromise between the parameters of laser processing and characteristics of nanostructured thin films of PVACOOH in terms of porosity and similar composition with those of starting material.
Keywords :
In vitro , Controlled drug release , Matrix-assisted pulsed laser evaporation , Porous polymers
