Author/Authors :
Ahmed، S R نويسنده Department of Obstetrics & Gynecology, Qassim College of Medicine, Saudia Arabia. , , Alzolibani، A A نويسنده Department of Dermatology, Qassim College of Medicine, Saudia Arabia. , , Al Robaeeb، A A نويسنده Department of Dermatology, Qassim College of Medicine, Saudia Arabia.. , , Hamed، H O نويسنده Department of Obstetrics & Gynecology, Qassim College of Medicine, Saudia Arabia , , Settin، A نويسنده Department of Pediatrics & Genetics, Qassim College of Medicine, Saudia Arabia. ,
Abstract :
Hirsutism is a common clinical condition that usually has a benign course. A genetic abnormality causing hirsutism is supported by the observation that different members of the same family are often affected.The goal of this study is to evaluate the genetic aspect of inheritance and consanguinity patterns of hirsute cases in Qassim region, Saudia Arabia. A total 83 hirsute patients were studied during one year duration. All patients underwent detailed history and thorough clinical evaluation. Ultrasonography and hormonal profiles were performed.The most common cause of hirsutism in this study was due to polycystic ovary (PCO) that was present in 52 patients (62.65%) followed by idiopathic hirsutism (IH) in 30 patients (36.14%) in addition to one case of late onset congenital adrenal hyperplasia. Acne was encountered in 34 (65.38%) of cases of PCO and in 13(43.33%) of cases of IH. Positive family history and consanguinity were encountered in 48(57.83%) and 49 (59.03%) cases respectively. Our study suggested that hirsutism is a familial disorder. Inheritance pattern appeared to be possible particular from the maternal followed by the paternal side of the family.
