Author/Authors :
Tende، J J.A نويسنده Department of Human Physiology, Faculty of Medicine, Ahmadu Bello University, Zaria, Nigeria. , , Eze، E.D. نويسنده Department of Human Physiology, Faculty of Medicine, Ahmadu Bello University, Zaria, Kaduna State, Nigeria. , , Tende ، Y.A. نويسنده Department of Pharmacology and Clinical pharmacy, Ahmadu Bello University, Zaria, Nigeria. , , Ugwu، M.N. نويسنده Department of Medical Biochemistry, Faculty of Basic Medical Sciences, Cross River University of Technology, Calabar, Nigeria. , , Shaibu، A. نويسنده Department of Human Physiology, Faculty of Medicine, Ahmadu Bello University, Zaria, Kaduna State, Nigeria. , , Onaadepo، O. نويسنده Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences University of Abuja, Abuja, Nigeria. , , Malgwi ، I.S. نويسنده Department of Human Physiology, Faculty of Medicine, Ahmadu Bello University, Zaria, Nigeria. ,
Abstract :
In this study, we evaluated the effect of aqueous ginger extract on sperm concentration in male wistar rats. A total of eighteen (18) apparently healthy male wistar rats were used. They were divided into three (3) groups of six (6) animals each as follows: Group 1: Served as the control and received distilled water, Group 2: Received 50 mg/kg b w of aqueous ginger extract and Group 3: received 100mg/kg of aqueous ginger extract respectively. The extract was administered to animals orally once daily for a period of twenty eight days. After the last day of treatment, animals from each group were euthanized and sperms cells collected from the caudal epididymis for sperm count evaluation. The results obtained revealed that the extract administered produced a significantly increased (p < 0.05) mean sperm count from 3.150 ± 0.253 to 3.80 ± 0.146 in the group that received 50 mg/kg and from 3.150 ± 0.253 to 4.917±0.26 in animals that received 100 mg/kg b w of the extract when compared to control group respectively. In conclusion, the present study showed that the aqueous extract of ginger may possess an androgenic activity; hence may have useful effects on spermatogenesis.
