• Title of article

    The Role of PML in Tumor Suppression

  • Author/Authors

    Paolo Salomoni، نويسنده , , Pier Paolo Pandolfi، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2002
  • Pages
    6
  • From page
    165
  • To page
    170
  • Abstract
    The PML gene, involved in the t(15;17) chromosomal translocation of acute promyelocytic leukemia (APL), encodes a protein which localizes to the PML-nuclear body, a subnuclear macromolecular structure. PML controls apoptosis, cell proliferation, and senescence. Here, we review the current understanding of its role in tumor suppression.
  • Journal title
    CELL
  • Serial Year
    2002
  • Journal title
    CELL
  • Record number

    1017645