Title of article
The Role of PML in Tumor Suppression
Author/Authors
Paolo Salomoni، نويسنده , , Pier Paolo Pandolfi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2002
Pages
6
From page
165
To page
170
Abstract
The PML gene, involved in the t(15;17) chromosomal translocation of acute promyelocytic leukemia (APL), encodes a protein which localizes to the PML-nuclear body, a subnuclear macromolecular structure. PML controls apoptosis, cell proliferation, and senescence. Here, we review the current understanding of its role in tumor suppression.
Journal title
CELL
Serial Year
2002
Journal title
CELL
Record number
1017645
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