Title of article :
Taking the Study of Cancer Cell Survival to a New Dimension
Author/Authors :
Tyler Jacks.، نويسنده , , Robert A. Weinberg، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2002
Pages :
3
From page :
923
To page :
925
Abstract :
Apoptosis plays a key role in the development of cancer and the response of tumor cells to therapeutic intervention. Recent work using three-dimensional cell culture models underscores the importance of the interactions between epithelial cells–both normal and malignant–and the extracellular matrix that surrounds them in informing life and death decisions. Research in this area is beginning to define the oncogenic pathways that can interfere with this process and the biochemical pathways that transmit signals from proper cell-matrix interactions to promote cell survival.
Journal title :
CELL
Serial Year :
2002
Journal title :
CELL
Record number :
1018070
Link To Document :
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