Title of article :
Coordinate Regulation of an Extended Chromosome Domain
Author/Authors :
Vincent D. Calhoun، نويسنده , , Michael Levine، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
([this issue of Cell]) describe the properties of a novel cis-regulatory DNA element, the global control region (GCR), which regulates gene expression over distances of several hundred kilobases at the mouse HoxD complex. The GCR provides an explanation for the colinear genetic linkage and expression of individual Hox genes within developing limbs.