Title of article :
The Secret Life of Histones
Author/Authors :
David A.F Gillespie، نويسنده , , Karen H Vousden، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2003
Abstract :
Recent evidence reveals an unexpected role for the linker histone H1.2 in DNA damage-induced apoptosis. DNA double strand breaks induce translocation of nuclear H1.2 to the cytoplasm, where it promotes release of cytochrome c from mitochondria by activating the Bcl-2 family protein, Bak.