Author/Authors :
Genie C. Leung، نويسنده , , Frank Sicheri، نويسنده ,
Abstract :
New work by Elia et al. in this issue of Cell reveals the molecular basis of phosphopeptide recognition by the polo domain and the domainʹs dual function to promote substrate recognition by targeting the kinase to subcellular structures and to autoregulate the adjacent protein kinase catalytic domain.