Title of article
Immortal Strands? Give Me a Break
Author/Authors
Peter M. Lansdorp، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2007
Pages
4
From page
1244
To page
1247
Abstract
The “immortal strand” hypothesis proposes that asymmetrically dividing stem cells selectively retain chromosomes containing “old” DNA to prevent accumulation of mutations. As I describe in this Essay, such a possibility seems unlikely. An alternative explanation is that asymmetric cell divisions and cell fate are codirected by epigenetic differences between sister chromatids.
Journal title
CELL
Serial Year
2007
Journal title
CELL
Record number
1018723
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