Title of article :
The Chromosomal Passenger Complex: One for All and All for One
Author/Authors :
Sandrine Ruchaud، نويسنده , , Mar Carmena، نويسنده , , William C. Earnshaw، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2007
Abstract :
The chromosomal passenger complex—composed of Aurora B kinase and its regulatory subunits INCENP, Survivin, and Borealin—modulates multiple events during mitosis. In this issue, report the crystal structure of the regulatory subunit complex and reveal how interactions between these proteins promote the targeting and function of the chromosomal passenger complex during mitosis.