Title of article :
The Meaning of Gene Positioning
Author/Authors :
Takumi Takizawa، نويسنده , , Karen J. Meaburn، نويسنده , , Tom Misteli، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
There is no doubt that genomes are organized nonrandomly in the nucleus of higher eukaryotes. But what is the functional relevance of this nonrandomness? In this Essay, we explore the biological meaning of spatial gene positioning by examining the functional link between the activity of a gene and its radial position in the nucleus.