• Title of article

    Abate and Switch: miR-145 in Stem Cell Differentiation

  • Author/Authors

    Raghu R. Chivukula، نويسنده , , Joshua T. Mendell، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    3
  • From page
    606
  • To page
    608
  • Abstract
    MicroRNAs have been implicated as regulators of embryonic stem (ES) cell self-renewal and pluripotency. In this issue, demonstrate that miR-145 facilitates ES cell differentiation by repressing the core pluripotency factors OCT4, SOX2, and KLF4, thereby silencing the self-renewal program.
  • Journal title
    CELL
  • Serial Year
    2009
  • Journal title
    CELL
  • Record number

    1019744