• Title of article

    Prion Topology and Toxicity

  • Author/Authors

    Adriano Aguzzi، نويسنده , , Andrew D. Steele، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2009
  • Pages
    3
  • From page
    994
  • To page
    996
  • Abstract
    Inactivation of mahogunin, an E3 ubiquitin ligase, causes a spongiform encephalopathy resembling prion disease. now report that prion proteins with aberrant topologies inactivate mahogunin, providing a plausible explanation for certain aspects of prion pathology.
  • Journal title
    CELL
  • Serial Year
    2009
  • Journal title
    CELL
  • Record number

    1019783