Title of article :
DNA Repair by the MRN Complex: Break It to Make It
Author/Authors :
Roland Kanaar and Claire Wyman، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2008
Abstract :
Genomic instability in ataxia telangiectasia-like disorder and Nijmegen breakage syndrome is due to disruption of the Mre11-Rad50-Nbs1 complex. and now reveal the importance of the nuclease activity of Mre11 for mammalian genome maintenance and present a molecular view of its active site.
