Title of article :
Integrins and Mutant p53 on the Road to Metastasis
Author/Authors :
Galina Selivanova، نويسنده , , Johanna Ivaska، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2009
Abstract :
Understanding how tumor cells invade tissues is key to developing drugs to block metastasis. In this issue, report that a mutant form of the tumor suppressor p53 in cancer cells boosts the endocytic recycling of the adhesion molecule integrin α5β1 and of epidermal growth factor receptor, promoting invasion and metastasis.
