Author/Authors :
George-Lucian Moldovan، نويسنده , , Alan D. DʹAndrea، نويسنده ,
Abstract :
Left unrepaired, DNA interstrand crosslinks represent impassable hurdles for DNA replication, and their removal is a complicated stepwise process involving a variety of enzymes. In a recent paper in Science, demonstrate that the Fanconi Anemia protein FANCD2 promotes multiple steps of the crosslink repair process.
