Title of article
Treating the Periphery to Ameliorate Neurodegenerative Diseases
Author/Authors
Peter H. Reinhart، نويسنده , , Jeffery W. Kelly and Carol V. Robinson، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2011
Pages
2
From page
813
To page
814
Abstract
Abnormalities in the kynurenine pathway are associated with neurodegenerative disorders. show that inhibition of kynurenine 3-monooxygenase in the bodyʹs periphery leads to an increase in kyneuric acid, a neuroprotective compound, in the brain. This intervention ameliorates neurodegeneration in mouse models of Alzheimerʹs disease and Huntingtonʹs disease.
Journal title
CELL
Serial Year
2011
Journal title
CELL
Record number
1020711
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