Author/Authors :
Mingshan Xue، نويسنده , , Nikolaos Giagtzoglou، نويسنده , , Hugo J. Bellen، نويسنده ,
Abstract :
Ca2+-triggered neurotransmitter release is characterized by two kinetically distinct components: a fast synchronous phase and a slow asynchronous phase. now report that double C2 domain (Doc2) proteins function as high-affinity Ca2+ sensors to specifically regulate the asynchronous component of neurotransmitter release.