Title of article :
FGF21 and the Second Coming of PPARγ
Author/Authors :
Li Qiang، نويسنده , , Domenico Accili، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
Peptide hormone fibroblast growth factor-21 (FGF21) has insulin-mimetic properties. Dutchak et al. now suggest that FGF21 also acts in an autocrine fashion in adipocytes and is required to mediate effects of the PPARγ agonist class of antidiabetic drugs. Does this new property improve FGF21ʹs fledgling clinical prospects or endorse a clinical resuscitation of PPARγ agonists?
