Title of article :
Deconstructing the Complexity of a Microenvironmental Niche
Author/Authors :
Daniela S. Krause، نويسنده , , David T. Scadden، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Pages :
2
From page :
16
To page :
17
Abstract :
Cells acquire their fate in vivo in the context of a complex microenvironmental “niche” comprised of heterologous cell types, signaling molecules, extracellular matrix, biophysical forces, and metabolic substrates. Now Calderón and Boehm report the “refunctionalization” of a defective thymic epithelial niche, offering insights into how signaling molecules may be hierarchically organized to direct differentiation outcomes.
Journal title :
CELL
Serial Year :
2012
Journal title :
CELL
Record number :
1021111
Link To Document :
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