Title of article :
Dna2 Offers Support for Stalled Forks
Author/Authors :
Mong Sing Lai، نويسنده , , Marco Foiani، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2012
Abstract :
The ATR and ATM checkpoint kinases preserve the integrity of replicating chromosomes by preventing the reversal of stalled and terminal replication forks. Hu et al. now show that the ATR pathway targets the Dna2 nuclease to process stalled forks and counteract fork reversal.
