Author/Authors :
Trevor D. Littlewood، نويسنده , , Peter Kreuzaler، نويسنده , , Gerard I. Evan، نويسنده ,
Abstract :
Myc is an enigma wrapped in a mystery. Attempts to identify Myc target genes, particularly in cancer, have been fraught with dead ends and context-specific functions. Lin et al. and Nie et al. address this conundrum by showing that Myc acts to amplify the output of existing transcriptionally active genes.