NEUTIT: a computer program for evaluating equivalence volumes and ionization constants in polar non-aqueous or partially aqueous media

A modified version of the EUTIT program, called NEUTIT, which accounts for potentiometric titrations in polar non-aqueous or partially aqueous media is developed. The program was applied to the titration data of several substances in three mixed solvents. The output of the program gives consistent and unbiased estimations of equivalence volumes and acidity constants. Good agreement between acidity constants evaluated from NEUTIT and the reported literature values is found in all cases. The program utilizes all titration data pairs which may be acquired from an automatic titrator unit.