Simultaneous determination of retinal, retinol and retinoic acid (all-trans and 13-cis) in cosmetics and pharmaceuticals at electrodeposited metal electrodes Original Research Article

The electrochemical behaviors of retinoids on glassy carbon and electrodeposited metal electrodes were investigated in various aqueous or nonaqueous containing supporting electrolytes, respectively. Retinal, retinol, all-trans-retinoic acid (all-trans-RA ) and 13-cis-retinoic acid (13-cis-RA) can be separated at the thin-film lead deposited glassy carbon electrode in 0.1 M tetrabutylammonium hydroxide. The electroreduction process is applied for the simultaneous quantitative determination of retinoids in cosmetics and pharmaceuticals. Comparison with results obtained from high performance liquid chromatography shows good agreement.