Detection and correction of interferences in spectroscopy techniques Original Research Article

By combining the apparent content curves method and the Youden method, we have developed a strategy for detecting constant and proportional errors in spectroscopy techniques. A method for elimination of spectral interferences (different of blank) is also proposed. To apply of this method there must be a matrix effect that varies with the amount of sample or a simulated matrix effect provided working under different experimental conditions that induce a variation of the analytical signal of the analyte. The proposed procedures have been applied to the determination of methyl orange in presence of phenol red, bromothymol blue and bromocresol purple.