Title of article
The Association Between Polymorphisms in Insulin and Obesity Related Genes and Risk of Colorectal Cancer
Author/Authors
Rezaei-Tavirani، Mostafa نويسنده , , Safaei، Akram نويسنده Gastroentrology and Liver Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Safaei, Akram , Zali، Mohammad Reza نويسنده Gastroentrology and Liver Diseases Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran ,
Issue Information
دوماهنامه با شماره پیاپی 0 سال 2013
Pages
7
From page
179
To page
185
Abstract
Colon cancer is the cancer of the large intestine (colon), which is located in the lower part of digestive system. Colon cancer is the third most common cancer in men and the second in women worldwide. Genetic background is thought to play a role in modulating individual risks of this cancer. Many studies support an association between insulin pathway gene polymorphisms and regulation of tumor cell biology in colorectal cancer. This review examines the role of polymorphisms of insulin and obesity pathway genes (IGFs, INS, INSR, ADIPOQ, ADIPOQR, LEP and LEPR) in development of colorectal cancer.
Journal title
Iranian Journal of Cancer Prevention(IJCP)
Serial Year
2013
Journal title
Iranian Journal of Cancer Prevention(IJCP)
Record number
1035611
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