Effect of hydrophilic–hydrophobic balance on biocompatibility of poly(methyl methacrylate) (PMMA)–hydroxyapatite (HA) composites

The purpose of this study is to put in evidence the correlation between hydrophilic/hydrophobic balance and biocompatibility of PMMA–HA composites, in order to select the best composites for futures clinical applications. For this purpose, PMMA–HA cements with different compositions were prepared and static contact angle measurements, water absorption and gingival fibroblasts cell culture were performed and discussed.