The drug delivery system of MCM-41 materials via co-condensation synthesis

The functional MCM-41 materials were prepared through co-condensation method, as compared postsynthesis and solvothermal processes were also used. The as-functionalized MCM-41 materials have been characterized by XRD, TEM, N2 adsorption and 29Si CP/MAS NMR. The modified materials have been used as drug-controlled delivery system of aspirin. The results showed that the release properties of this system were affected by functionalization degree and the distribution of functional groups on the pore wall surface of mesoporous materials, and the better delivery rate of MCM-41 materials would be obtained via co-condensation process.