Title of article :
New Chiral Ligands Derived from (S)-Leucine for the Enantioselective Addition of Diethylzinc to Aldehydes
Author/Authors :
Yasuhiro Kawanami، نويسنده , , Tomoko Mitsuie، نويسنده , , Misuzu Miki، نويسنده , , Takanobu Sakamoto، نويسنده , , Kazumi Nishitani، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
A new series of chiral β-amino alcohols derived from (S)-leucine has been synthesized. The amino alcohol possessing a piperidine ring and a phenethyl group on the carbinol carbon atom was found to be an efficient ligand to catalyze the enantioselective addition of diethylzinc to aromatic (up to 97% ee) and aliphatic (up to 95% ee) aldehydes.
Keywords :
chiral ligands , (S)-leucine , enantioselective addition
Journal title :
Tetrahedron
Journal title :
Tetrahedron
