A General Procedure to Enantiopure Conduritols: Sulfur-Mediated Synthesis of (+)-Conduritol B and (−)-Conduritol F Derivatives and of (−)-Conduritol E and F

We have demonstrated the generality of a simple procedure, synthesizing enantiomerically pure (+)-conduritol B and (−)-conduritol F derivatives, starting from d-mannitol and d-sorbitol, respectively. This method, slightly modified, can also be applied to the synthesis of unprotected conduritols: (−)-conduritol E and (−)-conduritol F were obtained.