Title of article
Development of a Method for the Preparation of α-Azido-Masked Acyl Cyanides, Synthetic Equivalents of N-Protected–C-Activated α-Amino Acids
Author/Authors
Hisao Nemoto، نويسنده , , Rujian Ma، نويسنده , , Touru Ibaragi، نويسنده , , Ichiro Suzuki، نويسنده , , Masayuki Shibuya، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
6
From page
1463
To page
1468
Abstract
A method for the preparation of α-azido-masked acyl cyanides as synthetic equivalents of N-protected–C-activated α-amino acids was developed using carbon–carbon bond formation between aldehydes and the Masked Acyl Cyanide Reagents, followed by sulfonylation and substitution by azide anion. This method was applied to the synthesis of d-threonine and l-allo-threonine derivatives.
Keywords
Cyanides , Threonine , acyl anion , Azides , Amino acids and peptides
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080620
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