Title of article :
Biosynthesis of Myxothiazol Z, the Ester-analog of Myxothiazol A in Myxococcus fulvus
Author/Authors :
Heinrich Steinmetz، نويسنده , , Edgar Forche، نويسنده , , Hans Reichenbach، نويسنده , , Gerhard H?fle، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Among myxobacteria only strains of Myxococcus fulvus are able to produce in addition to the well known myxothiazol A (1) an analog, myxothiazol Z (2), with an ester-type β-methoxyacrylate pharmacophore. Feeding experiments with labeled precursors established its biosynthesis from the amide (1) presumably via an O-methyl imidate (3).
Keywords :
antifungals , biogenesis , Labeling , Microorganisms
Journal title :
Tetrahedron
Journal title :
Tetrahedron
