Title of article
Biosynthesis of Myxothiazol Z, the Ester-analog of Myxothiazol A in Myxococcus fulvus
Author/Authors
Heinrich Steinmetz، نويسنده , , Edgar Forche، نويسنده , , Hans Reichenbach، نويسنده , , Gerhard H?fle، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
1681
To page
1684
Abstract
Among myxobacteria only strains of Myxococcus fulvus are able to produce in addition to the well known myxothiazol A (1) an analog, myxothiazol Z (2), with an ester-type β-methoxyacrylate pharmacophore. Feeding experiments with labeled precursors established its biosynthesis from the amide (1) presumably via an O-methyl imidate (3).
Keywords
antifungals , biogenesis , Labeling , Microorganisms
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1080645
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