Title of article :
Copper Catalyzed Conjugate Addition of Highly Functionalized Arylmagnesium Compounds to Enones
Author/Authors :
Greta Varchi، نويسنده , , Alfredo Ricci، نويسنده , , Gérard Cahiez، نويسنده , , Paul Knochel، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Highly functionalized arylmagnesium bromides are readily prepared by an iodine–magnesium exchange reaction. In the presence of catalytic amounts of copper(I) salts and chlorotrimethylsilane, they add to various enones leading to the conjugate addition products in 66–89% yield.
Keywords :
Copper catalysis , Conjugate addition , polyfunctional organomagnesium compounds
Journal title :
Tetrahedron
Journal title :
Tetrahedron
