Title of article :
Synthesis of Transition State Analogue Inhibitors for Purine Nucleoside Phosphorylase and N-Riboside Hydrolases
Author/Authors :
Gary B. Evans، نويسنده , , Richard H. Furneaux، نويسنده , , Graeme J. Gainsford، نويسنده , , Vern L. Schramm، نويسنده , , Peter C. Tyler، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Syntheses of the ‘Immucillins’, potent aza-C-nucleoside inhibitors of purine nucleoside phosphorylase are reported as well as those of 5-deoxy-, 5-deoxyfluoro- and 2-deoxy- analogues and others having modified bases.
Keywords :
Carbohydrate mimetics , Enzyme inhibitors , Nucleosides , Purines
Journal title :
Tetrahedron
Journal title :
Tetrahedron