Author/Authors :
Xiaowu Yang، نويسنده , , Jun-wu Su، نويسنده , , Daxue Liu، نويسنده , , Hengshan Wang، نويسنده , , Jianheng Shen، نويسنده , , Chaoshan Da، نويسنده , , Rui Wang، نويسنده , , Albert S.C. Chan، نويسنده ,
Abstract :
Enantiomeric BINOL has been anchored to aminomethylated polystyrene resin at the 3- and 3,3′-positions of BINOL respectively. The resulting functionalized polymers 4 and 7 have been used as chiral ligands in the Ti-catalytic enantioselective addition of diethylzinc to aldehydes. Compared with the homogeneous ligands 5 and 8 in the same reaction, the polymer-supported ligands 4 and 6 gave, in some cases, higher enantioselectivity. The conformational inflexibility of the ligands was analyzed to illustrate the results.
