• Title of article

    Rigid Dipeptide Mimetics. Stereocontrolled Synthesis of All Eight Stereoisomers of 2-Oxo-3-(N-Cbz-amino)-1-azabicyclo[4.3.0]nonane-9-carboxylic Acid Ester

  • Author/Authors

    Johann Mulzer، نويسنده , , Frank Schülzchen، نويسنده , , Jan-W. Bats، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    10
  • From page
    4289
  • To page
    4298
  • Abstract
    Stereopure 2-oxo-3-(N-Cbz-amino)-1-azabicyclo[4.3.0]nonane-9-carboxylic acid (AZABIC) methyl and ethyl esters (14a/b and 23a/b, respectively) have been synthesized from readily available (R)- and (S)-pyroglutamic esters 1 and 15. Altogether all eight possible stereoisomers of this type of compound have been prepared in gram quantities.
  • Keywords
    Allylation , peptide mimetics , Amino acids , stereoselection
  • Journal title
    Tetrahedron
  • Serial Year
    2000
  • Journal title
    Tetrahedron
  • Record number

    1080922

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1080922