Author/Authors :
Atsushi Nishida، نويسنده , , Irie Miyoshi، نويسنده , , Yukie Ogasawara، نويسنده , , Shinji Nagumo، نويسنده , , Norio Kawahara، نويسنده , , Mayumi Nishida، نويسنده , , Hiroaki Takayanagi، نويسنده ,
Abstract :
A new skeletal rearrangement of cyclopentanones with pentynyl side chains into hydroazulene compounds via a radical process was developed. The presence of a triethylsilyloxy group at the α-position of the cyclopentanone was found to increase the reactivity. Except for this, there was no limitation of the reaction. The reaction was also applied to synthetic studies of damsinic acid, which was isolated from Ambrosia ambrosioides (Cav.) Payne along with damsin.
Keywords :
radical skeletal rearrangement , hydroazulene compound , damsinic acid , cyclopentanone derivatives
