Title of article
The Polonovski–Potier Reaction of Berbine N-Oxides. Synthesis of 8-Hydroxymethyl and 8-Methylberbines
Author/Authors
Rafael Suau، نويسنده , , Francisco Najera، نويسنده , , Rodrigo Rico، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
11
From page
9713
To page
9723
Abstract
The Polonovski–Potier reaction of trans and cis berbines N-oxides was studied. The 8-cyano derivative obtained from trans N-oxides were used to synthesize 8-hydroxymethyl and 8-methyl berbines. This procedure was applied to the stereocontroled synthesis of (8R, 14S)-(−)-8-methylcanadine from (14S)-(−)-canadine.
Keywords
Alkaloids , Polonovski reaction , isoquinolines , protoberberines
Journal title
Tetrahedron
Serial Year
2000
Journal title
Tetrahedron
Record number
1081497
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