Title of article
A model study for the total synthesis of (±)-scopadulin: stereoselective construction of the A/B ring system with desired functionalities
Author/Authors
S.M. Abdur Rahman، نويسنده , , Hiroaki Ohno، نويسنده , , Hitoshi Yoshino، نويسنده , , Norifumi Satoh، نويسنده , , Mahoto Tsukaguchi، نويسنده , , Kazuo Murakami، نويسنده , , Chuzo Iwata، نويسنده , , Naoyoshi Maezaki، نويسنده , , Tetsuaki Tanaka، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
8
From page
127
To page
134
Abstract
A model study toward the total synthesis of (±)-scopadulin is described. Stereocontrolled synthesis of the A/B ring system with desired functionalities was achieved by stereoselective cyanation of a bicyclic enone with Et2AlCN, diastereoselective construction of a quaternary carbon at C-4 with LDA-BOMCl, and conversion of the cyano group into a methyl group.
Keywords
diastereoselection , copper and compounds , conjugate addition deamination
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1081567
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