Title of article :
Synthesis of a 3-aminopiperidin-2,5-dione as a conformationally constrained surrogate of the Ala-Gly dipeptide
Author/Authors :
M.Angels Estiarte، نويسنده , , Anna Diez، نويسنده , , Mario Rubiralta، نويسنده , , Richard F.W Jackson، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
The preparation of the Boc-{Ala-Gly}-OBn pseudopeptide 4 is reported. The key intermediate, aminoester 5b, was obtained by a cross-coupling reaction of alaninezinc iodide 6 and the thioester of glycine 9.
Keywords :
aminolactam , diketopiperidine , peptide mimetic , ?-turn mimetic , dioxopiperidine
Journal title :
Tetrahedron
Journal title :
Tetrahedron
