Author/Authors :
Alberto Avenoza، نويسنده , , Carlos Cativiela، نويسنده , , Jes?s H Busto، نويسنده , , Miguel A Fern?ndez-Recio، نويسنده , , Jes?s M Peregrina، نويسنده , , Fernando Rodriguez، نويسنده ,
Abstract :
This report describes a new synthetic route to 7-azabicyclo[2.2.1]heptane-1-carboxylic acid (Ahc), a constrained proline analogue, in which the key step is the Diels–Alder reaction using methyl 2-benzamidoacrylate as dienophile.
Keywords :
Diels–Alder reactions , aza compounds , bicyclic heterocyclic compounds , amino acids and derivatives
