Title of article
Alkylation of carbonyl compounds in the TiCl4-promoted reaction of trimethylsilyl enol ethers with epoxides
Author/Authors
Gojko Lali?، نويسنده , , ?eljko Petrovski، نويسنده , , Danica Galoni?، نويسنده , , Radomir Matovic، نويسنده , , Radomir N. Saicic، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
9
From page
583
To page
591
Abstract
Titanium tetrachloride promoted reaction of trimethylsilyl enol ethers with ethylene oxide affords homoaldol type products in moderate/good yields. Monosubstituted epoxides react regioselectively: the nucleophilic attack of the enolate occurs at the more substituted position of propene oxide whereas epichlorohydrin reacts at the less substituted end.
Keywords
Epoxides , enol ethers , Mukaiyama reactions , titanium and compounds , Alkylation
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1081618
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