Title of article
Microwave-mediated regioselective synthesis of novel pyrimido[1,2-a]pyrimidines under solvent-free conditions
Author/Authors
Jean Jacques Vanden Eynde، نويسنده , , Nancy Hecq، نويسنده , , Olga Kataeva، نويسنده , , C. Oliver Kappe، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
7
From page
1785
To page
1791
Abstract
Ethyl 2-amino-4-aryl-1,4-dihydro-6-phenylpyrimidine-5-carboxylates readily react, under microwave irradiation and solvent-free conditions, with 3-formylchromone or diethyl (ethoxymethylene)malonate to yield novel pyrimido[1,2-a]pyrimidines. The structure of the final products, deduced from the spectral data and confirmed by X-ray analysis, allows us to suggest reaction pathways.
Keywords
Microwave , solvent-free conditions , Pyrimidine , Biginelli compounds
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1081746
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