Title of article
A stereocontrolled synthesis of 2R-benzyl-5S-tert-butoxycarbonylamino-4R-(tert-butyldimethylsilanyloxy)-6-phenyl-hexanoic acid (Phe–Phe hydroxyethylene dipeptide isostere)
Author/Authors
Alan Nadin، نويسنده , , José M S?nchez L?pez، نويسنده , , Joseph G. Neduvelil، نويسنده , , Steven R Thomas، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
1861
To page
1864
Abstract
2R-Benzyl-5S-tert-butoxycarbonylamino-4R-(tert-butyldimethylsilanyloxy)-6-phenyl-hexanoic acid, a hydroxyethylene dipeptide isostere corresponding to Phe–Phe, has been synthesized in a practical, stereocontrolled fashion from (l)-phenylalanine.
Keywords
Alzheimerיs disease , ?-secretase , hydroxyethylene dipeptide isostere
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1081756
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