Title of article :
A stereocontrolled synthesis of 2R-benzyl-5S-tert-butoxycarbonylamino-4R-(tert-butyldimethylsilanyloxy)-6-phenyl-hexanoic acid (Phe–Phe hydroxyethylene dipeptide isostere)
Author/Authors :
Alan Nadin، نويسنده , , José M S?nchez L?pez، نويسنده , , Joseph G. Neduvelil، نويسنده , , Steven R Thomas، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
2R-Benzyl-5S-tert-butoxycarbonylamino-4R-(tert-butyldimethylsilanyloxy)-6-phenyl-hexanoic acid, a hydroxyethylene dipeptide isostere corresponding to Phe–Phe, has been synthesized in a practical, stereocontrolled fashion from (l)-phenylalanine.
Keywords :
Alzheimerיs disease , ?-secretase , hydroxyethylene dipeptide isostere
Journal title :
Tetrahedron
Journal title :
Tetrahedron
