Title of article :
Synthesis of 3-alkyl-1-isoindolinones by alkylation of a benzotriazolyl substituted N-dimethylamino-phthalimidine
Author/Authors :
Eric Deniau، نويسنده , , Dieter Enders، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
A convenient and versatile synthesis of 3-alkyl-2,3-dihydro-1H-isoindol-1-ones (isoindolinones) based upon sequential metalation, alkylation alpha to nitrogen and C,N-deprotection from 3-benzotriazolyl-2-dimethylamino-phthalimidine is described.
Keywords :
Alkylation , Benzotriazole , carbanions , Hydrazines , Lactams
Journal title :
Tetrahedron
Journal title :
Tetrahedron