Title of article
A short synthesis of 5-methoxy-2,2-dimethyl-2H-1-benzopyran-6-propanoic acid methyl ester
Author/Authors
Geneive E Henry، نويسنده , , Helen Jacobs، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
5335
To page
5338
Abstract
5-Methoxy-2,2-dimethyl-2H-1-benzopyran-6-propanoic acid methyl ester was prepared in five steps and approximately 20% overall yield from 2,4-dihydroxybenzaldehyde. The two key reactions are the chromenylation between the unchelated hydroxyl group and C-3 of the resbenzaldehyde and the demethoxycarbonylation-alkylation of dimethyl malonate with a quaternary ammonium iodide.
Keywords
Alkylation , benzopyran , chromene , Decarboxylation , dealkylation
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082126
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