Title of article
(Cyanomethyl)trimethylphosphonium iodide as reagent for the intermolecular S-alkylation of thiols with alcohols
Author/Authors
Florencio Zaragoza، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
4
From page
5451
To page
5454
Abstract
Treatment of mixtures of thiols and primary aliphatic alcohols with (cyanomethyl)trimethylphosphonium iodide leads to the clean formation of unsymmetric thioethers. The required phosphonium iodide is simple to prepare and stable towards air and moisture. This new synthesis of thioethers yields crude products of high purity and should be suitable for parallel solution-phase chemistry.
Keywords
Alcohols , Alkylation , Thioethers , phosphonium salts
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082140
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