Title of article :
Convenient synthesis of 5-perfluoroalkylsubstituted isoxazoles
Author/Authors :
Peng Weimin، نويسنده , , Zhu Shizheng، نويسنده , , Jin Guifang، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2001
Abstract :
5-Perfluoroalkylsubstituted isoxazoles are prepared readily from the reaction of nitrile oxide generated in situ from RCH2NO2, TEA and POCl3 with ethyl 3-perfluoroalkyl-3-pyrrolidino-acrylates, which were obtained by treatment of α-perfluoroalkyl ethyl acetate with pyrrolidine in the presence of base.
Keywords :
Synthesis , 1 , fluorine-containing isoxazole , 3 dipolar cycloaddition , Nitrile oxide , Enamine
Journal title :
Tetrahedron
Journal title :
Tetrahedron
