Title of article
Synthesis of 1,1-dioxopenicillanoyloxymethyl 6-[d-α-(benzylideneaminophenylacetamido)]penicillanate and analogs. New intermediates in the preparation of sultamicillin
Author/Authors
J. Carlos del Pozo، نويسنده , , Eduardo Alonso، نويسنده , , Fernando L?pez-Ortiz، نويسنده , , Félix Fern?ndez-Mar??، نويسنده , , Miguel Bayod Jasanada، نويسنده , , Javier Gonz?lez، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2001
Pages
6
From page
6209
To page
6214
Abstract
The synthesis of benzylidene imines of sultamicillin and analogs 1 is described. These new compounds showed high stability and were prepared under very mild conditions and high yields. Furthermore, they are convenient starting materials for the preparation of sultamicillin 5 (important prodrug of ampicillin and sulbactam) as its base form, by deprotection of the amino group with Girard reagents.
Keywords
Antibiotics , Ampicillin , Girard reagents , sultamicillin , Sulbactam
Journal title
Tetrahedron
Serial Year
2001
Journal title
Tetrahedron
Record number
1082225
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