• Title of article

    Regioselective palladium-catalyzed cross-coupling reactions in the synthesis of novel 2,3-disubstituted thiophene derivatives

  • Author/Authors

    Raquel Pereira، نويسنده , , Beatriz Iglesias، نويسنده , , Angel R. de Lera، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2001
  • Pages
    11
  • From page
    7871
  • To page
    7881
  • Abstract
    A reactivity optimization study of the palladium-catalyzed cross-coupling reactions of 2,3-dibromothiophene and organometallic reagents has been conducted. Regioselective coupling at the C2 position, accomplished most notably by Suzuki coupling, was combined with a Stille reaction at C3 using Fuʹs modification, to afford the 2,3-disubstituted thiophene derivatives.
  • Keywords
    Stille reactions , Thiophenes , Heterocycles , Suzuki reactions , Sonogashira reactions
  • Journal title
    Tetrahedron
  • Serial Year
    2001
  • Journal title
    Tetrahedron
  • Record number

    1082400